Name:
Schneider, Anna, Dr.
Date of Birth:
November 26, 1981
Address:
Universität Bayreuth; Dept. of Biopolymers
Universitätsstraße 30, 95447 Bayreuth
Phone: +49 921 55-3869
 
Email: anna.schneider@uni-bayreuth.de

Current Position
from 11/2011 Ph.D. student at the Department of Biopolymers University of Bayreuth
Ph.D. thesis: Structure function analysis and molecular mechanisms of inhibition of retroviral reverse transcriptases.

Education
10/2011 Master of Science: Biochemistry and Molecular Biology, U Bayreuth
Master Thesis: Prof. B. M. Wöhrl, Department of Biopolymers, U Bayreuth
9/2009 Bachelor of Science: Biochemistry, U Bayreuth
Bachelor Thesis: Prof. Dr. K. H. Hoffmann, Department of Animal Ecology, U Bayreuth

Additional Information
2-10/2012 Ph.D. student in the Graduate School BIGSS with the topic: "Lead Structures of Cell Function" within Elite Network of Bavaria
from 9/2012 Ph.D. student in the doctoral program Molecular Biosciences (BayNAT Bayreuth Graduate School of Biosciences)
from 6/2013 membership in the interdisciplinary programme of the University of Bayreuth Graduate School

Poster Presentations
  "BIGSS Bayreuther Strukturtage" 25-27. July 2012
Title: Characterization of Retroviral Resistance Mechanism against Azidothymidine.
  International Workshop on Antiviral Drug Resistance 3-7. Juni 2013
Title: Inhibition of Foamy Virus Reverse Transcriptase by Human Immunodeficiency Virus Type 1 Ribonuclease H Inhibitors.

Oral Presentations
  "30. Rabensteiner Kolleg" in Pottenstein 7-9. June 2012
Title: The AZT Resistance Mechanism in the Simian Foamy Virus.
  International Summer School in Sardinia, Cagliari 30. September-4. Oktober 2012
Title: Mechanism of Foamy Virus Azidothymidine-Resistance.

10 Important Publications
(Members of the Dept. of Biopolymers: boldface)
[1]     Spannaus R, Schneider A, Hartl M, Wöhrl BM, Bodem J. Foamy viral Gag p71/p68 cleavage is required for template switch of the reverse transcriptase. J. Virol. 2013 7774-6. doi:10.1128/JVI.00833-13.
[2]     Schneider A, Peter D, Schmitt J, Leo B, Richter F, Rösch P, Wöhrl BM, Hartl MJ. Domain structure and requirements for enzyma tic activities of foamy virus Protease-Reverse Transcriptase. Proteins. 2014 375-85. doi: 10.1002/prot.24394.
[3]     Corona A, Schneider A, Schweimer K, Rösch P, Wöhrl BM, Tramontano E. Inhibition of Foamy Virus Reverse Transcriptase by Human Immunodeficiency Virus Type 1 Rnase H Inhibitor. Antimicrob Agents Chemother. 2014 4086-4093. doi: 10.1128/AAC.00056-14.
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Research Interests
  • Structure analysis, domain organization and enzymatic characterization of the simian foamy virus enzyme protease-reverse transcriptase (PR-RT) from macaques (SFVmac)
  • Mechanisms of resistance against azidothymidine (AZT) in the retroviruses SFVmac and the human immunodeficiency virus type 1 (HIV-1)
  • Inhibitor binding studies with the retroviral ribonuclease H (RNase H) domain of the reverse transcriptase